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IDH1 Inhibitor 7-d<sub>2</sub>

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2654

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

2526

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-150238S

IDH1 Inhibitor 7-d2	Isocitrate Dehydrogenase (IDH)	Cancer
IDH1 Inhibitor 7-d₂ is the deuterium labeled IDH1 Inhibitor 7 (HY-150238). IDH1 Inhibitor 7 is an *IDH1* inhibitor with an IC₅₀ of less than 100 nM ^[1] ^[2].

HY-13972

Mutant IDH1 inhibitor

2 Publications Verification

Isocitrate Dehydrogenase (IDH) Cancer

Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC₅₀ of < 72 nM.

*Mutant IDH1* inhibitor** 2 Publications Verification	Isocitrate Dehydrogenase (IDH)	Cancer
Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC₅₀ of < 72 nM.

HY-41648

IDH1 Inhibitor 8	Isocitrate Dehydrogenase (IDH)	Cancer
IDH1 Inhibitor 8 (91) is isocitrate dehydrogenase 1 *(IDH1)* inhibitor. IDH1 Inhibitor 8 can be used for the research of cancer ^[1].

HY-112601

IDH1 Inhibitor 1	Isocitrate Dehydrogenase (IDH)	Cancer
IDH1 Inhibitor 1 is a potent, orally bioavailable, brain-penetrant and selective mutant *IDH1* inhibitor with IC₅₀s of 0.021 μM, 0.045 μM, and 2.52 μM for IDH1 ^R132H, IDH1 ^R132C, and IDH1 ^WT, respectively ^[1]. Anticancer activity ^[1].

HY-143306

IDH1 Inhibitor 5	Isocitrate Dehydrogenase (IDH)	Cancer
IDH1 Inhibitor 5 (compound 2) is an *IDH1* (isocitrate dehydrogenase 1) inhibitor. IDH1 Inhibitor 5 inhibits MOG cells and wild-type IDH1 glioma cells with expressing exogenous mutant IDH1 R132H protein with IC₅₀s of 64.4 and 34.9 nM, respectively ^[1].

HY-107977

IDH1 Inhibitor 3	Isocitrate Dehydrogenase (IDH)	Cancer
IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC₅₀ of 45 nM for IDH1 ^R132H ^[1].

HY-150238

IDH1 Inhibitor 7

Isocitrate Dehydrogenase (IDH) Cancer

IDH1 Inhibitor 7 (Compound 88) is an IDH1 inhibitor with an IC₅₀ of less than 100 nM ^[1].

IDH1 Inhibitor 7	Isocitrate Dehydrogenase (IDH)	Cancer
IDH1 Inhibitor 7 (Compound 88) is an *IDH1* inhibitor with an IC₅₀ of less than 100 nM ^[1].

HY-128661

IDH1 Inhibitor 2	Isocitrate Dehydrogenase (IDH)	Metabolic Disease
IDH1 Inhibitor 2 (compound 13) is a potent wild-type IDH1 inhibitor via a direct covalent modification of His315, with an IC₅₀ of 110 nM ^[1].

HY-RS06527

IDH1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IDH1 Human Pre-designed siRNA Set A contains three designed siRNAs for IDH1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IDH1 Human Pre-designed siRNA Set A IDH1 Human Pre-designed siRNA Set A

HY-RS06528

Idh1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Idh1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Idh1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Idh1 Mouse Pre-designed siRNA Set A Idh1 Mouse Pre-designed siRNA Set A

HY-RS06529

Idh1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Idh1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Idh1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Idh1 Rat Pre-designed siRNA Set A Idh1 Rat Pre-designed siRNA Set A

HY-149359

*IHMT-IDH1-053*	Isocitrate Dehydrogenase (IDH)	Cancer
IHMT-IDH1-053 (compound 16) is a highly selectivity and irreversible *IDH1-mutant* inhibitor with an IC₅₀ of 4.7 nM for IDH1 R132H. IHMT-IDH1-053 displays high selectivity against IDH1 mutants over IDH1 wt and IDH2 wt/mutants. IHMT-IDH1-053 inhibits 2-hydroxyglutarate (2-HG) production in IDH1 R132H mutant transfected 293T cells (IC₅₀=28 nM). IHMT-IDH1-053 binds to the IDH1 R132H protein in the allosteric pocket adjacent to the NAPDH binding pocket through a covalent bond with residue Cys269. IHMT-IDH1-053 inhibits the proliferation of HT1080 cell line and primary AML cells which both bear IDH1 R132 mutants ^[1].

HY-131312

LY3410738 Mutant IDH1-IN-6	Isocitrate Dehydrogenase (IDH)	Cancer
Mutant IDH1-IN-6 is a potent, selective and orally active mutant isocitrate dehydrogenase (IDH) inhibitor with IC₅₀s of 6.27 nM, 3.71 nM, 36.9 nM and 11.5 nM for IDH1 R132H, IDH1 R132C, IDH2 R140Q and IDH2 R172K mutant enzymes, respectively. Mutant IDH1-IN-6 is less active at inhibiting the IDH wild-type enzymes ^[1].

HY-12475

*Mutant IDH1-IN-1* 2 Publications Verification	Isocitrate Dehydrogenase (IDH)	Cancer
Mutant IDH1-IN-1 is a mutant-selective *IDH1* inhibitor with with IC₅₀s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.

HY-114459

*Mutant IDH1-IN-4*	Isocitrate Dehydrogenase (IDH)	Cancer
Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC₅₀ values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells ^[1].

HY-18717

*Mutant IDH1-IN-2* 2 Publications Verification	Isocitrate Dehydrogenase (IDH)	Cancer
Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in Fluorescence biochemical assay.

HY-145594

Safusidenib AB-291; DS-1001	Isocitrate Dehydrogenase (IDH)	Cancer
Safusidenib (AB-291; DS-1001) is an orally bioavailable, selective mutant *IDH1* inhibitor. Safusidenib strongly inhibits mutant IDH1 but not wild-type IDH1. Safusidenib impairs tumor activity in chondrosarcoma ^[1]. Safusidenib exhibits activity against *IDH1R132H, and IDH1R132C* with IC₅₀s of 15, and 130 nM in assays without any preincubation, respectively ^[2].

HY-110144

TC-E 5008	Isocitrate Dehydrogenase (IDH)	Cancer
TC-E 5008 is a potent mutant IDH1 inhibitor with K_i values of 190 nM and 120 nM for R132H and R132C IDH1 mutants, respectively. TC-E 5008 exhibits very weak activity against WT-IDH1 with a K_i value of 12.3 μM. TC-E 5008 has anti-proliferative activity on multiple ER positive breast cancer cell lines ^[1] ^[2].

HY-121736

AGI-12026 AGI-026	Isocitrate Dehydrogenase (IDH)	Neurological Disease
AGI-12026 is brain-penetrant dual inhibitor of mutant IDH1 and 2. AGI-12026 shows partial inhibition of the IDH1-R132H homodimer as allosteric modulators. AGI-12026 has the potential for research of glioma ^[1].

HY-104036

IDH-305	Isocitrate Dehydrogenase (IDH)	Cancer
IDH-305 is an orally available, mutant-selective and brain-penetrant *IDH1* inhibitor that targets IDH1 (R132) mutation. IDH-305 exhibits greater than 200 fold selectivity for mutant IDH1 isoforms vs. WT (IC₅₀= 27 nM (IDH1 ^R132H), 28 nM (IDH1 ^R132C), 6.14 µM (IDH1 ^WT)) ^[1] ^[2].

HY-112289

IDH889	Isocitrate Dehydrogenase (IDH)	Cancer
IDH889 is an orally available, brain penetrant, allosteric and mutant specific inhibitor of isocitrate dehydrogenase 1 (IDH1). IDH889 has potent selectivity for IDH1 R132* mutations, with IC₅₀s of 0.02 μM, 0.072 μM and 1.38 μM for IDH1 ^R132H, IDH1 ^R132C and IDH1 ^wt, respectively. IDH889 shows potent cellular inhibition of R-2-hydroxyglutarate (2-HG) production with an IC₅₀ of 0.014 μM ^[1].

HY-112289B

*(1R)-IDH889*	Isocitrate Dehydrogenase (IDH)	Cancer
(1R)-IDH889 is the isomer of IDH889 (HY-112289), and can be used as an experimental control. IDH889 is an orally available, brain penetrant, allosteric and mutant specific inhibitor of isocitrate dehydrogenase 1 (IDH1). IDH889 has potent selectivity for IDH1 R132* mutations, with IC₅₀s of 0.02 μM, 0.072 μM and 1.38 μM for IDH1 ^R132H, IDH1 ^R132C and IDH1 ^wt, respectively. IDH889 shows potent cellular inhibition of R-2-hydroxyglutarate (2-HG) production with an IC₅₀ of 0.014 μM ^[1].

HY-N0328

alpha-Mangostin 3 Publications Verification α-Mangostin	Reactive Oxygen Species Apoptosis Bacterial Fungal Virus Protease	Cancer
alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-114226

Olutasidenib 1 Publications Verification FT-2102	Isocitrate Dehydrogenase (IDH)	Inflammation/Immunology Cancer
Olutasidenib (FT-2102) is a highly potent, orally active, brain penetrant and selective inhibitor of mutant Isocitrate dehydrogenase 1 (IDH1), with IC₅₀ values of 21.2 nM and 114 nM for IDH1- R132H and IDH1- R132C, respectively . Olutasidenib (FT-2102) is under the study in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) ^[1] ^[2].

HY-19540

GSK864 4 Publications Verification	Isocitrate Dehydrogenase (IDH)	Cancer
GSK864 is an isocitrate dehydrogenase 1 (IDH1) mutant inhibitor; inhibits IDH1 mutants R132C, R132H, and R132G with IC₅₀ values of 8.8, 15.2 and 16.6 nM.

HY-18948

GSK321 1 Publications Verification
GSK321 is a potent inhibitor of mutant *isocitrate dehydrogenase 1 (IDH1) enzymes. GSK321 has high inhibitory and selectivity for mutant IDH1* enzymes. GSK321 can be used for the research of acute myeloid leukemia ^[1] ^[2].

HY-104042

Vorasidenib 3 Publications Verification AG-881	Isocitrate Dehydrogenase (IDH)	Cancer
Vorasidenib (AG-881) is an orally available, brain penetrant second-generation dual mutant isocitrate dehydrogenases 1 and 2 (mIDH1/2) inhibitor. Vorasidenib (AG-881) exhibits nanomolar inhibition of (D)-2-hydroxyglutarate (D-2-HG), and the IC₅₀ ranges of 0.04~22 nM against IDH1 R132C, IDH1 R132G, IDH1 R132H and IDH1 R132S and 7~14 nM against IDH2 R140Q and 130 nM against IDH2 R172K ^[1] ^[2].

HY-143234

mIDH1-IN-1	Isocitrate Dehydrogenase (IDH)	Cancer
mIDH1-IN-1 (compound 43) is a potent and selective *mIDH1* (mutant isocitrate dehydrogenases 1) inhibitor, with an IC₅₀ of 961.5 nM. mIDH1-IN-1 potently inhibits intracellular *2-HG* (2-hydroxyglutarate) production in HT1080 cells, with an EC₅₀ of 208.6 ± 8.0 nM. mIDH1-IN-1 shows a significant anti-proliferation activity on IDH1 mutant-U-87 cells, with an IC₅₀ of 41.8 nM. mIDH1-IN-1 is an antitumor agent, and can be used for IDH1 mutated solid tumors research ^[1].

HY-100020

BAY-1436032

3 Publications Verification

Isocitrate Dehydrogenase (IDH) Cancer

BAY-1436032 is a novel pan-mutant isocitrate dehydrogenase 1 (IDH1) inhibitor.

BAY-1436032 3 Publications Verification	Isocitrate Dehydrogenase (IDH)	Cancer
BAY-1436032 is a novel pan-mutant isocitrate dehydrogenase 1 (IDH1) inhibitor.

HY-128888

(R,R)-GSK321	Isocitrate Dehydrogenase (IDH)	Cancer
(R,R)-GSK321 is a wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor with an IC₅₀ value of 120 nM. (R,R)-GSK321 as a mutant R132H IDH1 inhibitor, is an isomer of GSK321 with some wild-type cross reactivity ^[1].

HY-N0328R

alpha-Mangostin (Standard) α-Mangostin (Standard)	Fungal Reactive Oxygen Species Bacterial Apoptosis Virus Protease	Cancer
alpha-Mangostin (Standard) is the analytical standard of alpha-Mangostin. This product is intended for research and analytical applications. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-18082

AGI-5198

10+ Cited Publications

IDH-C35
Isocitrate Dehydrogenase (IDH) Cancer

AGI-5198 (IDH-C35) is a potent and selective mutant IDH1 ^R132H inhibitor with an IC₅₀ of 0.07 μM.
HY-136686

IDH-C227

Isocitrate Dehydrogenase (IDH) Cancer

IDH-C227 is a potent and selective IDH1 ^R132H inhibitor. IDH-C227 has anticancer effcts ^[1].

AGI-5198 10+ Cited Publications IDH-C35	Isocitrate Dehydrogenase (IDH)	Cancer
AGI-5198 (IDH-C35) is a potent and selective mutant IDH1 ^R132H inhibitor with an IC₅₀ of 0.07 μM.

IDH-C227	Isocitrate Dehydrogenase (IDH)	Cancer
IDH-C227 is a potent and selective IDH1 ^R132H inhibitor. IDH-C227 has anticancer effcts ^[1].

HY-129545

DS-1001b 1 Publications Verification	Isocitrate Dehydrogenase (IDH)	Cancer
DS-1001b is an orally active, blood-brain permeable, potent *IDH-1* (isocitrate dehydrogenase-1) mutant inhibitor. DS-1001b has antitumor activity ^[1] ^[2] .

HY-N12390

Alternaphenol B2	Isocitrate Dehydrogenase (IDH)	Cancer
Alternaphenol B2 is a selective *IDH1* inhibitor from the coral-derived fungus Parengyodontium album SCSIO SX7W11. Alternaphenol B2 shows inhibitory activity against isocitrate dehydrogenase mutant R132H (IDH1m), with IC₅₀ values of 41.9 μM ^[1].

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase ^[1].

HY-128888B

(S,R)-GSK321	Isocitrate Dehydrogenase (IDH)	Cancer
(S,R)-GSK321 is a potent, selective mutant *IDH1* inhibitor with IC₅₀ values of 2.9, 3.8, 4.6 and 46 nM for R132G, R132C, R132H and WT IDH1, respectively, and >100-fold selectivity over IDH2. (S,R)-GSK321 induces decrease in intracellular 2-HG, abrogation of the myeloid differentiation block and induction of granulocytic differentiation at the level of leukemic blasts and more immature stem-like cells. (S,R)-GSK321can be used for research of acute myeloid leukemia (AML) and other cancers ^[1].

HY-R00008

hsa-let-7d-3p mimic	MicroRNA	Cancer
hsa-let-7d-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-let-7d-3p mimic hsa-let-7d-3p mimic

HY-RI00008

hsa-let-7d-3p inhibitor	MicroRNA
hsa-let-7d-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-let-7d-3p inhibitor hsa-let-7d-3p inhibitor

HY-112499S

*Menaquinone-7-d7* Vitamin K2-7-d<sub>7sub>; Vitamin K2(35)-d<sub>7sub>; Vitamin MK-7-d<sub>7sub>	Isotope-Labeled Compounds	Cardiovascular Disease
Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-B0511S2

Biotin-d2 Vitamin B7-d<sub>2sub>; Vitamin H-d<sub>2sub>; D-Biotin-d<sub>2sub>	Endogenous Metabolite	Metabolic Disease
Biotin-d₂ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-R00008A

hsa-let-7d-3p agomir	MicroRNA
hsa-let-7d-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-let-7d-3p agomir hsa-let-7d-3p agomir

HY-B0511S

Biotin-d2-1 Vitamin B7 d<sub>2sub>-1; Vitamin H d<sub>2sub>-1; D-Biotin d<sub>2sub>-1	Endogenous Metabolite	Metabolic Disease
Biotin-d₂-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-RI00008A

hsa-let-7d-3p antagomir	MicroRNA
hsa-let-7d-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-let-7d-3p antagomir hsa-let-7d-3p antagomir

HY-B0389S26

D-Glucose-d2-2 Glucose-d<sub>2sub>-2; D-(+)-Glucose-d<sub>2sub>-2; Dextrose-d<sub>2sub>-2	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose-d₂-2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling mol

HY-122814

Hedgehog IN-1

Hedgehog Others Neurological Disease Cancer

Hedgehog IN-1 (Compound 7d) is an inhibitor for Hedgehog protein with IC₅₀ of 70 nM ^[1].

HY-100753

STAT3-IN-1 5+ Cited Publications
STAT3-IN-1 (compound 7d) is an excellent, selective and orally active STAT3 inhibitor, with IC₅₀ values of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 (compound 7d) induces tumor cells apoptosis ^[1].

HY-Y0418S4

Dulcite-d2 Dulcitol-d<sub>2sub>; Melampyrit-d<sub>2sub>; NSC 1944-d<sub>2sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
Dulcite-d₂ is the deuterium labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-B0400S9

D-Sorbitol-d2-2 Sorbitol-d<sub>2sub>-2; D-Glucitol-d<sub>2sub>-2	Endogenous Metabolite	Others
D-Sorbitol-d₂-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di

Cat. No.	Product Name	Type

HY-W127572

Glycerol-d8

1,2,3-Propanetriol-d<sub>8sub>; Glycerin-d<sub>8sub>
Biochemical Assay Reagents

Glycerol-d₈ is the deuterium labeled Glycerol[1].

HY-109541S2

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d9 DMPC-d<sub>9sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₉ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d58 DMPC-d<sub>58sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₅₈ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S1

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d4 DMPC-d<sub>4sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₄ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S3

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d13 DMPC-d<sub>13sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₁₃ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S4

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d63 DMPC-d<sub>63sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₆₃ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S5

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d67 DMPC-d<sub>67sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₆₇ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S6

(Rac)-1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d72 (Rac)-DMPC-d<sub>72sub>	Drug Delivery
(Rac)-1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₇₂ is deuterium labeled (Rac)-1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-ph

HY-W127840

Ethylene-d4-diamine

1,1,2,2-tetradeuterioethane-1,2-diamine-d<sub>4sub>
Biochemical Assay Reagents

Ethylene-d₄-diamine is the deuterium labeled Ethylene-diamine[1].

HY-E70152

ST6 Sialyltransferase 4 EC:2.4.3.7; ST6GALNAC4; SIAT3-C	Enzyme Substrates
ST6 Sialyltransferase 4 (EC:2.4.3.7; ST6GALNAC4; SIAT3-C; SIAT3C; SIAT7-D; SIAT7D) catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. ST6 Sialyltransferase 4 promotes hepatocellular carcinogenesis by inducing abnormal glycosylation. ^[1].

Cat. No.	Product Name	Target	Research Area

HY-P2274

Argifin	Parasite	Infection
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively ^[1].

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Peptides	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent **Plasmodium subtilisin-like protease 1 (SUB1)** inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively ^[1].

HY-P3426

BACE1-IN-10

Beta-secretase Cancer

BACE1-IN-10 is a potent BACE1 Inhibitor. BACE1-IN-10 shows sub-micromolar activity against recombinant BACE1 (rBACE1) ^[1].

HY-P5856

αA-Conotoxin PIVA	nAChR	Neurological Disease
αA-Conotoxin PIVA is a selective mouse musclenAChR inhibitor with IC₅₀ for adult and fetal mouse musclenAChR sub> values are 2.3 nM and 22 nM respectively. αA-Conotoxin PIVA can be used in the study of neurological diseases.

HY-P3809

[D-Pro2,D-Phe7,D-Trp9] Substance P	Peptides	Neurological Disease
[D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P (HY-P0201) analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly ^[1] ^[2].

HY-N2466

Melanotan I 1 Publications Verification MT-I; [Nle4,D-Phe7]-α-MSH	Melanocortin Receptor	Neurological Disease Cancer
Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for the research of sun-induced skin cancer, melanoma, inflammation and male erectile dysfunction ^[1] ^[2] .

HY-P3881

(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P

Neurokinin Receptor Neurological Disease

(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P is a selective NK₁ receptor antagonist ^[1].

HY-P4679

(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) E2078	Opioid Receptor	Neurological Disease
(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) (E-2078), a stable Dynorphin A (1–8) (HY-P2159) analog, is a kappa opioid receptor (KOR) agonist ^[1].

HY-W010452S1

3-Hydroxybutyric acid-13C4 sodium β-Hydroxybutyric acid-¹³C<sub>4sub> sodium	Endogenous Metabolite	Metabolic Disease
3-Hydroxybutyric acid- ¹³C₄ (sodium) is the ¹³C labeled 3-Hydroxybutyric acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium is a metabolite that is elevated in type I diabetes, and can modulate the properties of membrane lipids[1].

HY-P3659

(D-Phe7)-α-MSH

Melanocortin Receptor Cancer

(D-Phe7)-α-MSH is an α-MSH analogue ^[1].

HY-P5493

D-Arg-[Hyp3,Thi5,8,D-Phe7]-Bradykinin	Peptides	Others
D-Arg-[Hyp3,Thi5,8,D-Phe7]-Bradykinin is a biological active peptide. (inhibited bradykinin-induced contractions concentration dependently; bradykinin B2 receptor antagonist)

HY-P4540

(D-Leu7)-LHRH	Peptides	Others
(D-Leu7)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development ^[1].

HY-P4578

(D-Trp6,D-Leu7)-LHRH	Peptides	Others
(D-Trp6,D-Leu7)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development ^[1].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0328

alpha-Mangostin 3 Publications Verification α-Mangostin	Structural Classification other families Xanthones Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal Virus Protease
alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-125833

Alpha-Naphthoflavone 5 Publications Verification	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[1] ^[2] .

HY-N0328R

alpha-Mangostin (Standard) α-Mangostin (Standard)	Structural Classification other families Xanthones Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	Fungal Reactive Oxygen Species Bacterial Apoptosis Virus Protease
alpha-Mangostin (Standard) is the analytical standard of alpha-Mangostin. This product is intended for research and analytical applications. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-N12390

Alternaphenol B2	Structural Classification Microorganisms Source classification Phenols Polyphenols	Isocitrate Dehydrogenase (IDH)
Alternaphenol B2 is a selective *IDH1* inhibitor from the coral-derived fungus Parengyodontium album SCSIO SX7W11. Alternaphenol B2 shows inhibitory activity against isocitrate dehydrogenase mutant R132H (IDH1m), with IC₅₀ values of 41.9 μM ^[1].

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). ^[1].

HY-W011474

Geranylgeraniol	Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[1] ^[2] .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively ^[1].

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations ^[1].

HY-N0662

Amentoflavone Maximum Cited Publications 7 Publications Verification Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Disease Research Fields Selaginella tamariscina (P. Beauv.) Spring Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[1] ^[2] .

HY-B0504S

Creatinine-d3 NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-113038B

α-Hydroxyglutaric acid 2-Hydroxyglutarate; 2-Hydroxyglutaric acid; 2-Hydroxypentanedioic acid	Structural Classification Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer	Histone Demethylase Endogenous Metabolite
α-Hydroxyglutaric acid (2-Hydroxyglutarate) is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases ^[1].

HY-113038A

α-Hydroxyglutaric acid disodium 2-Hydroxyglutarate disodium; 2-Hydroxyglutaric acid disodium; 2-Hydroxypentanedioic acid disodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Histone Demethylase Endogenous Metabolite
α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases ^[1].

HY-100542

D-α-Hydroxyglutaric acid disodium 2 Publications Verification Disodium (R)-2-hydroxyglutarate	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Cancer	Reactive Oxygen Species ATP Synthase mTOR Endogenous Metabolite
D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid disodium is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a K_i of 10.87 mM. D-α-Hydroxyglutaric acid disodium increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid disodium binds and inhibits ATP synthase and inhibits mTOR signaling ^[1] ^[2] .

HY-113038

D-α-Hydroxyglutaric acid (R)-2-Hydroxyglutarate; (R)-2-Hydroxyglutaric acid; (R)-2-Hydroxypentanedioic acid	Classification of Application Fields Neurological Disease Anti-aging Source classification Endocrine diseases Endogenous metabolite Immune System Disorder Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Inflammation/Immunology Cancer	Reactive Oxygen Species ATP Synthase mTOR Endogenous Metabolite
D-α-Hydroxyglutaric acid ((R)-2-Hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a K_i of 10.87 mM. D-α-Hydroxyglutaric acid increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling ^[1] ^[2] .

Species:	Virus (1) Human (13)
Tag:	GFP (3) His (11) SUMO (1) Strep (4) Trx (1)
Source:	HEK293 (5) E. coli Cell-free (4) Sf9 insect cells (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P70214

	IDH1 Protein, Human (HEK293, His, Solution) rHuIsocitrate dehydrogenase [NADP] cytoplasmic/IDH1, His; Isocitrate Dehydrogenase [NADP] Cytoplasmic; IDH; Cytosolic NADP-Isocitrate Dehydrogenase; IDP; NADP(+)-Specific ICDH; Oxalosuccinate Decarboxylase; IDH1; PICD	Human	HEK293
	The IDH1 protein catalyzes the oxidative decarboxylation of isocitrate to generate 2-oxoglutarate, which is utilized by enzymes such as phytoacyl-CoA dioxygenase. IDH1 Protein, Human (HEK293, His, Solution) is the recombinant human-derived IDH1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IDH1 Protein, Human (HEK293, His, Solution) is 414 a.a., with molecular weight of ~48 kDa.

HY-P70214A

	IDH1 Protein, Human (HEK293, C-His) rHuIsocitrate dehydrogenase [NADP] cytoplasmic/IDH1, His; Isocitrate Dehydrogenase [NADP] Cytoplasmic; IDH; Cytosolic NADP-Isocitrate Dehydrogenase; IDP; NADP(+)-Specific ICDH; Oxalosuccinate Decarboxylase; IDH1; PICD	Human	HEK293
	The IDH1 protein catalyzes the oxidative decarboxylation of isocitrate to generate 2-oxoglutarate, which is utilized by enzymes such as phytoacyl-CoA dioxygenase. IDH1 Protein, Human (HEK293, C-His) is the recombinant human-derived IDH1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IDH1 Protein, Human (HEK293, C-His) is 414 a.a., with molecular weight of ~48 kDa.

HY-P74650

	*PC4/SUB1 Protein, Human (His)* Activated RNA polymerase II transcriptional coactivator p15; PC4; p14; sub1; RPO2TC1	Human	E. coli
	The PC4/SUB1 protein acts as a multifunctional coactivator that cooperates with TAF to promote functional interactions between upstream activators and the general transcription machinery. Its role extends to the potential stability of multiprotein transcription complexes. PC4/SUB1 Protein, Human (His) is the recombinant human-derived PC4/SUB1 protein, expressed by E. coli , with N-His labeled tag. The total length of PC4/SUB1 Protein, Human (His) is 127 a.a., with molecular weight of ~19 kDa.

HY-P702197

	ABCD3 Protein, Human (Cell-Free, His) ATP-binding cassette sub-family D member 3; 70 kDa peroxisomal membrane protein; PMP70	Human	E. coli Cell-free
	ABCD3 is a member of the ATP-binding cassette (ABC) family. ABCD3 Protein, Human (Cell-Free, His) is the recombinant human-derived ABCD3 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of ABCD3 Protein, Human (Cell-Free, His) is 659 a.a., with molecular weight of 81.5 kDa.

HY-P7621

	ABCB5 Protein, Human (Trx) rHuABCB5, N-Trx; ATP-binding cassette sub-family B member 5; P-glycoprotein ABCB5; ABCB5	Human	E. coli
	ABCB5, N-Trx Protein, Human is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma.

HY-P72012

	ABCD1 Protein, Human (Cell-Free, His) ABC42; Abcd1; ABCD1_HUMAN; Adrenoleukodystrophy protein; ALD; Aldgh; ALDP; AMN; ATP binding cassette; sub family D ALD; ; member 1; ATP-binding cassette sub-family D member 1; OTTHUMP00000025960; OTTMUSP00000019283; RGD1562128; RP23 373N8.2; X linked adrenoleukodystrophy ALD; gene homolog	Human	E. coli Cell-free
	ABCD1, Human (His) is one of the four ATP-binding cassette (ABC) proteins in subfamily D. Dysfunction of ABCD1 causes neurodegenerative disorder X-linked adrenoleukodystrophy (X-ALD).

HY-P702196

	ABCD2 Protein, Human (Cell-Free, His) ATP-binding cassette sub-family D member 2; Adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein; hALDR	Human	E. coli Cell-free
	ABCD2 protein is an ATP-dependent transporter in the ABC family that promotes the transport of very long chain fatty acids (VLCFA)-CoA into peroxisomes and exhibits fatty acyl-CoA thioesterase (ACOT) and ATPase activities. Its substrate specificity overlaps with ABCD1, including a clear preference for shorter VLCFA (C22:0) and polyunsaturated fatty acids (PUFA) such as C22:6-CoA and C24:6-CoA. ABCD2 Protein, Human (Cell-Free, His) is the recombinant human-derived ABCD2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of ABCD2 Protein, Human (Cell-Free, His) is 740 a.a., with molecular weight of 89.3 kDa.

HY-P702195

	ABCB8 Protein, Human (Cell-Free, His, SUMO) Mitochondrial potassium channel ATP-binding subunit; ATP-binding cassette sub-family B member 8, mitochondrial; ABCB8; Mitochondrial ATP-binding cassette 1; M-ABC1; Mitochondrial sulfonylurea-receptor; MITOSUR	Human	E. coli Cell-free
	ABCB8 is the ATP-binding subunit of mitochondrial potassium channels and cooperates with CCDC51/MITOK to form mitoK (ATP) channels in the inner mitochondrial membrane. This complex promotes ATP-dependent potassium currents. ABCB8 Protein, Human (Cell-Free, His, SUMO) is the recombinant human-derived ABCB8 protein, expressed by E. coli Cell-free , with N-6*His, N-SUMO labeled tag. The total length of ABCB8 Protein, Human (Cell-Free, His, SUMO) is 656 a.a., with molecular weight of 87 kDa.

HY-P72069

	ABCC1 Protein, Human (His) ABC 29; ABC29; ABCC 1; ABCC; Abcc1; ATP binding cassette sub family C CFTR/MRP; member 1; ATP binding cassette sub-family C member 1; ATP binding cassette subfamily C member 1; ATP binding cassette transporter variant ABCC1delta ex13; ATP binding cassette transporter variant ABCC1delta ex13&14; ATP binding cassette transporter variant ABCC1delta ex25; ATP binding cassette transporter variant ABCC1delta ex25&26; ATP binding cassette, sub-family C CFTR/MRP; , member 1; ATP-binding cassette sub-family C member 1; DKFZp686N04233; DKFZp781G125; GS X; GSX; Leukotriene C4; transporter; LTC4 transporter; MRP 1; MRP; MRP1; MRP1_HUMAN; Multidrug resistance associated protein 1; Multidrug resistance protein; Multidrug resistance-associated protein 1; Multiple drug resistance associated protein; Multiple drug resistance protein 1	Human	E. coli
	ABCC1, Human (His) is a multitasking ATP-binding cassette (ABC) transporter. ABCC1, Human plays a part in inflammatory and other immunological diseases, age-related macular degeneration, cardiovascular disease, and certain neurological disorders as well as tumor progression.

HY-P701354

	ABCC4 Protein, Human (HEK293, GFP, Strep, His) ABCC4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B; Multidrug resistance-associated protein 4	Human	HEK293
	ABCC4 Protein, an ATP-binding cassette (ABC) family member, actively transports endogenous compounds (cAMP, cGMP, bile acids) and xenobiotics from cells. Its versatility extends to glutathione conjugates (LTC4, LTB4) and drug metabolites, mediating cotransport of bile acids with reduced glutathione. ABCC4's function includes resistance to anticancer agents like methotrexate, highlighting its role in cellular communication and drug transport. ABCC4 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived ABCC4 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of ABCC4 Protein, Human (HEK293, GFP, Strep, His) is 1325 a.a., .

HY-P701355

	bABCC1 Protein, Human (HEK293, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Human	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of bABCC1 Protein, Human (HEK293, GFP, Strep, His) is 1530 a.a., .

HY-P701356

	bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Human	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag and E1454Q, , , , mutation. The total length of bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is 1530 a.a., .

HY-P79454

	ISG15 E1/UBE1L Protein, Human (sf9, His, Strep) Ubiquitin-like modifier-activating enzyme 7; UBA7; Ubiquitin-activating enzyme 7; D8; Ubiquitin-activating enzyme E1 homolog; UBE1L; UBE2	Human	Sf9 insect cells
	The ISG15 E1/UBE1L protein initiates ubiquitination by adenylating the C-terminal glycine of ubiquitin with ATP to form a thioester bond with its cysteine residue. This produces ubiquitin-E1 thioester and free AMP. ISG15 E1/UBE1L Protein, Human (sf9, His, Strep) is the recombinant human-derived ISG15 E1/UBE1L protein, expressed by Sf9 insect cells , with N-8*His, N-Strep labeled tag. The total length of ISG15 E1/UBE1L Protein, Human (sf9, His, Strep) is 1011 a.a., .

Cat. No.	Product Name	Chemical Structure

HY-150238S

IDH1 Inhibitor 7-d2

IDH1 Inhibitor 7-d₂ is the deuterium labeled IDH1 Inhibitor 7 (HY-150238). IDH1 Inhibitor 7 is an IDH1 inhibitor with an IC₅₀ of less than 100 nM ^[1] ^[2].
HY-B0511S

Biotin-d2-1

Biotin-d₂-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-112499S

Menaquinone-7-d7

Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-B0511S2

Biotin-d2

Biotin-d₂ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-B0389S26

D-Glucose-d2-2
D-Glucose-d₂-2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling mol

HY-Y0418S4

Dulcite-d2

Dulcite-d₂ is the deuterium labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-B0400S9

D-Sorbitol-d2-2
D-Sorbitol-d₂-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di

HY-B0389S22

D-Glucose-13C2,d2
D-Glucose- ¹³C₂,d₂ is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical si

HY-B0389S5

D-Glucose-d2
D-Glucose-d₂2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0141AS1

Alpha-Estradiol-d2
Alpha-Estradiol-d₂ is the deuterium labeled Alpha-Estradiol. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia[1].

HY-107352S

Fosfenopril-d7

Fosfenopril-d₇ is deuterium labeled Fosfenopril.

HY-107542S2

Oleoylethanolamide-d2
Oleoylethanolamide-d₂ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

HY-77839S1

Cortodoxone-d2

Cortodoxone-d₂ is the deuterium labeled Cortodoxone. Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone)[1].
HY-Y0747S1

1-Iodobenzene-d2

1-Iodobenzene-d₂ is the deuterium labeled 1-Iodobenzene[1].
HY-107327S

Carazolol-d7

Carazolol-d₇ is the deuterium labeled Carazolol[1].
HY-133712S1

Yonkenafil-d7

Yonkenafil-d₇ (Tunodafil-d₇) is deuterium labeled Yonkenafil.
HY-Y0376S

DMPA-d7

DMPA-d₇ is the deuterium labeled DMPA[1].
HY-N7745S

Glucosylsphingosine-d7

Glucosylsphingosine-d₇ is deuterium labeled Glucosylsphingosine.

HY-13632S

Exemestane-d2
Exemestane-d₂ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].

HY-B0246S1

Carbamazepine-d2

Carbamazepine-d₂ is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent.

HY-B0234S1

Estrone-d2
Estrone-d₂ is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-N0378S4

D-Mannitol-d2

D-Mannitol-d₂ is the deuterium labeled D-Mannitol.

HY-N1150S6

Thymidine-d2
Thymidine-d₂ is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1

HY-W460871S

Apramycin-d7 acetate

Apramycin-d₇ (acetate) (Nebramycin II-d₇ (acetate)) is a deuterium labeled compound.

HY-D0711S2

Indocyanine green-d7
Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography ^[1].

HY-B0141S3

Estradiol-d2
Estradiol-d₂ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].

HY-B0389S4

D-Glucose-d1-2
D-Glucose-d1-2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-W338294S3

2'-Deoxycytidine-d2 monohydrate

2'-Deoxycytidine-d₂ (monohydrate) is the deuterium labeled (R)-2,3-Dihydroxypropanal[1].

HY-B0389S23

D-Glucose-d2-1
D-Glucose-d₂-1 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling mol

HY-B0021S

Doxifluridine-d2

Doxifluridine-d₂ is the deuterium labeled Doxifluridine[1]. Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.

HY-13677S

6-Mercaptopurine-d2
6-Mercaptopurine-d₂ is the deuterium labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent[1][2].

HY-13623S

Entecavir-d2

Entecavir-d₂ is the deuterium labeled Entecavir. Entecavir (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.

HY-N0650S7

L-Serine-d2
L-Serine-d₂ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-W004282S2

Undecanoic acid-d2
Undecanoic acid-d₂ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-B0400S4

D-Sorbitol-d2
D-Sorbitol-d₂ is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and diet

HY-B0228S6

Adenosine-d2
Adenosine-d₂ is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio

HY-B0141S6

Estradiol-d2-1
Estradiol-d₂-1 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3][4].

HY-B0648S1

Medroxyprogesterone-d7

Medroxyprogesterone-d₇ is deuterium labeled Medroxyprogesterone.

HY-W013812S2

Ethyl linoleate-d2
Ethyl linoleate-d₂ (Linoleic Acid ethyl ester-d₂; Mandenol-d₂) is the deuterium labeled Ethyl linoleate (HY-W013812). Ethyl linoleate (Linoleic Acid ethyl ester) inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators ^[1] ^[2].

HY-Y0069S1

N-Acetylglycine-d2
N-Acetylglycine-d₂ (Aceturic acid-d₂; Acetamidoacetic acid-d₂) is the deuterated labeled N-Acetylglycine (HY-Y0069). N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics ^[1].

HY-W337116S

Phenyl isopropylcarbamate-d7

Phenyl isopropylcarbamate-d₇ isopropylcarbamate-d₇ is the deuterium labeled Phenyl isopropylcarbamate[1].

HY-Y0921S1

(±)-1,2-Propanediol-d2
(±)-1,2-Propanediol-d₂ is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents.

HY-16637S

Folic acid-d2
Folic acid-d₂ (Vitamin B9-d₂) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-N0682S1

Pyridoxine-d2 hydrochloride
Pyridoxine-d₂ (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

HY-B0234S4

Estrone-d2-1
Estrone-d₂-1 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-B1203S1

Fludrocortisone-d2

Fludrocortisone-d₂ is the deuterium labeled Fludrocortisone. Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity.

HY-B0166S6

L-Ascorbic acid-d2
L-Ascorbic acid-d₂ is the deuterium labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a colla

HY-A0281S3

4-Phenylbutyric acid-d2
4-Phenylbutyric acid-d₂ is the deuterium labeled 4-Phenylbutyric acid[1]. 4-Phenylbutyric acid (4-PBA) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research.

HY-116152S2

Cipepofol-d6-2
Cipepofol-d₆-2 (Ciprofol-d₆-2; HSK3486-d₆-2) is deuterium labeled Cipepofol (HY-116152). Cipepofol (HSK3486), a psychomotor stabilizing agent, is a gamma-aminobutyric acid (GABA) receptor potentiator.

HY-B0022S

Flutamide-d7

Flutamide-d₇ is deuterium labeled Flutamide.

Cat. No.	Product Name	Application	Reactivity

HY-P80995

IDH1 Antibody	WB, IHC-P, IP	Human, Mouse, Rat
IDH1 Antibody is an unconjugated, approximately 47 kDa, rabbit-derived, anti-IDH1 monoclonal antibody. IDH1 Antibody can be used for: WB, IHC-P, IP expriments in human, mouse, rat background without labeling.

HY-P80527

ABCB5 Antibody (YA836) ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5	WB, ICC/IF	Human
ABCB5 Antibody (YA836) is a non-conjugated and Mouse origined monoclonal antibody about 139 kDa, targeting to ABCB5 (8D2). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

HY-P80772

P Glycoprotein Antibody p-pg; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243	WB	Human
P Glycoprotein Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 141 kDa, targeting to P Glycoprotein. It can be used for WB assays with tag free, in the background of Human.

HY-P81118

MRP2/ABCC2 Antibody multidrug resistance-associated protein2; ABC30; ABCC2; ATP binding cassette sub family C (CFTR/MRP) member 2; ATP binding cassette subfamily C member 2; Canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter 1; CMOAT; CMOAT1; cMRP; DJS; KIAA1010; MRP 2; MRP-2; MRP2; Multidrug resistance associated protein 2; MRP2_HUMAN; ATP-binding cassette sub-family C member 2; Multidrug resistance-associated protein 2.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse, Rat,
MRP2/ABCC2 Antibody is an unconjugated, approximately 174 kDa, rabbit-derived, anti-MRP2/ABCC2 polyclonal antibody. MRP2/ABCC2 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, background without labeling.

HY-P81267

Cytokeratin 7 Antibody (YA950) CK 7; CK-7; ck7; Cytokeratin 7; Cytokeratin-7; Cytokeratin7; D15Wsu77e; K2C7; K2C7_HUMAN; K7; Keratin 55k type ii cytoskeletal; Keratin 7; Keratin simple epithelial type 1 k7; Keratin type II cytoskeletal 7	WB, ICC/IF	Human

HY-P81267A

Cytokeratin 7 Antibody (YA951) CK 7; CK-7; ck7; Cytokeratin 7; Cytokeratin-7; Cytokeratin7; D15Wsu77e; K2C7; K2C7_HUMAN; K7; Keratin 55k type ii cytoskeletal; Keratin 7; Keratin simple epithelial type 1 k7; Keratin type II cytoskeletal 7	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat

HY-P81267B

Cytokeratin 7 Antibody (YA952) CK 7; CK-7; ck7; Cytokeratin 7; Cytokeratin-7; Cytokeratin7; D15Wsu77e; K2C7; K2C7_HUMAN; K7; Keratin 55k type ii cytoskeletal; Keratin 7; Keratin simple epithelial type 1 k7; Keratin type II cytoskeletal 7	WB, ICC/IF, IP	Human

Cat. No.	Product Name		Classification

HY-B0216S

Ethynyl Estradiol-d4 17α-Ethynylestradiol-d<sub>4sub>; Ethynylestradiol-d<sub>4sub>		Alkynes
Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0216S2

Ethynyl Estradiol-13C2 17α-Ethynylestradiol-¹³C<sub>2sub>; Ethynylestradiol-¹³C<sub>2sub>		Alkynes
Ethynyl Estradiol- ¹³C₂ is the ¹³C-labeled Ethynyl Estradiol. Ethynyl Estradiol-13C2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-17413S

Zidovudine-d3 Azidothymidine-d<sub>3sub>; AZT-d<sub>3sub>; ZDV-d<sub>3sub>		Azide
Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-50896S

Erlotinib-d6 CP-358774-d<sub>6sub>; NSC 718781-d<sub>6sub>; OSI-774-d<sub>6sub>		Alkynes
Erlotinib-d₆ (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0110S

Gestodene-d6 SHB 331-d<sub>6sub>; WL 70-d<sub>6sub>		Alkynes
Gestodene-d₆is the deuterium labeled Gestodene. Gestodene(SHB 331) is a progestogen hormonal contraceptive[1][2]. Gestodene-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-G0018S

Norgestimate metabolite norelgestromin-d6 17-Deacetyl norgestimate-d<sub>6sub>; 17-Deacylnorgestimate-d<sub>6sub>		Alkynes
Norgestimate metabolite norelgestromin-d₆ is the deuterium labeled Norgestimate metabolite norelgestromin. Norelgestromin is a metabolite of Norgestimate, which is a progestin or synthetic progestogen. Norgestimate metabolite norelgestromin-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-50896S1

Erlotinib-13C6 CP-358774-¹³C<sub>6sub>; NSC 718781-¹³C<sub>6sub>; OSI-774-¹³C<sub>6sub>		Alkynes
Erlotinib- ¹³C₆ is a ¹³C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].

HY-12008S1

Erlotinib-13C6 hydrochloride CP-358774-¹³C<sub>6sub> hydrochloride; NSC 718781-¹³C<sub>6sub> hydrochloride; OSI-774-¹³C<sub>6sub> hydrochloride		Alkynes
Erlotinib- ¹³C₆ (hydrochloride) is the ¹³C labeled Erlotinib Hydrochloride[1]. Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM[2]. Erlotinib-13C6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-17413S1

Zidovudine-13C,d3 Azidothymidine-¹³C,d<sub>3sub>; AZT-¹³C,d<sub>3sub>; ZDV-¹³C,d<sub>3sub>		Azide
Zidovudine- ¹³C,d₃ is the ¹³C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-13C,d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-B0554S

Norethindrone-d6 Norethisterone-d<sub>6sub>		Alkynes
Norethindrone-d₆ is the deuterium labeled Norethindrone. Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea. Norethindrone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0257S

Levonorgestrel-d8 D-Norgestrel-d<sub>8sub>		Alkynes
Levonorgestrel-d₈ is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives[1][2]. Levonorgestrel-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-14605BS

Rasagiline-13C3 mesylate racemic AGN1135-¹³C<sub>3sub>; TVP1012-¹³C<sub>3sub> racemic		Alkynes
Rasagiline- ¹³C₃ (mesylate racemic) is a ¹³C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B1710S

Norethindrone acetate-d8 19-Norethindrone acetate-d<sub>8sub>		Alkynes
Norethindrone acetate-d₈ is the deuterium labeled Norethindrone acetate. Norethindrone acetate is a female hormone used for the research of endometriosis[1]. Norethindrone acetate-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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